• The studies from several laboratories suggest that

  2019-06-29

  

  The studies from several laboratories suggest that miR-34 family members are the direct targets of TP53, and their upregulation can induce cancer cell apoptosis and cell-cycle arrest. It has been found that miR-34 is associated with prognosis, carcinogenesis, and survival of various cancers, includi

• It is possible that this contradiction may be due

  2019-06-29

  

  It is possible that this contradiction may be due to referral bias in the studies of Brugada et al. [20,21]. Second, it is possible that time of day influences the results of PES. The magnitude of ST-segment elevation in the right precordial leads in BS varies spontaneously over days and during the

• Beneficial interventions will require collaboration between

  2019-06-28

  

  Beneficial interventions will require collaboration between medical, veterinary, agricultural, social, environmental, and wildlife scientists. Veterinary medicine intersects with all of these disciplines and for years has promoted the concept of One Health as a technique for promotion of collaborati

• Human ether a go go related gene HERG

  2019-06-28

  

  Human-ether-a-go-go-related gene (HERG) encodes the α-subunit of rapidly-activating delayed-rectifier potassium PF-8380 that generate IKr. This outward potassium current is elicited during the plateau phase of action potentials and is required for repolarization [4]. After being translated in the en

• molecular weight In addition the TAA treated groups show htt

  2019-06-27

  

  In addition, the TAA-treated groups showed a significant reduction in body weight with significantly increased liver weights and sizes compared to control rats, but NJ cotreatment reversed those defects (Table 1). The reduction in body weights could be attributed to the toxic effect of TAA throughou

• br Future potential cardiac examinations for long duration

  2019-06-27

  

  Future potential cardiac examinations for long-duration spaceflights Currently available treatments for emergency cases in spaceflight Astronaut Crew Medical Officers (CMO) aboard the ISS receive 40–70h of medical training, including CPR training, within 18 months preceding their mission (Fig

• br Material and methods br

  2019-06-27

  

  Material and methods Results Discussion Previously, various small studies reported that CRT is an effective therapy in patients with NAHF [7,10–15]. These studies demonstrated favorable outcomes in patients treated with CRT, including the ability to wean patients from intravenous inotropes

• OS is Executive Director of

  2019-06-27

  

  OS is Executive Director of the INDEPTH Network. PB is Director of the WHO Collaborating Centre for Verbal Autopsy and chairs the Scientific Advisory Committee of the INDEPTH Network. The INDEPTH Network is grateful for core funding from Sida, the Wellcome Trust, and the William & Flora Hewlett Foun

• Sin embargo la mayor a de

  2019-06-27

  

  Sin embargo, la mayoría de los aventureros se quedó en la ensoñación, pues no logró hacerse de caudales, ni alcanzó encomiendas; de hecho, hacia 1540 y aun años después, el número de encomenderos en el gran Perú (hoy Perú, Bolivia y Ecuador) jamás rebasó los 500, indudablemente una minoría de la pob

• The BrS ECG is often

  2019-06-27

  

  The BrS ECG is often widely dynamic, with ST segment elevations that fluctuate from hour to hour, day to day, and month to month. Diurnal variation shows that events occur more frequently at night during periods of high vagal tone [2]. In some patients, the use of frequent ECGs or 12-lead ambulatory

• Based on these preliminary clinical results with low dose

  2019-06-27

  

  Based on these preliminary clinical results with low-dose, intermittent zoledronic acid, Hu et al. conducted a randomized phase II clinical study in order to clarify the role of metronomic low-dose zoledronic acid. Sixty breast cancer patients with bone metastases were randomized to receive either 1

• ERS and BrS are thought

  2019-06-27

  

  ERS and BrS are thought to represent 2 manifestations of the JWSs. Both syndromes are associated with vulnerability to development of polymorphic VT and VF leading to SCD [1–3,15] in young adults with no apparent structural Bufexamac disease and occasionally to sudden infant death syndrome [25–27].

• En Am rica Latina los a os noventa constituyen la

  2019-06-27

  

  En América Latina, los años noventa constituyen la década en la que los reclamos en términos de políticas de identidad en torno fludarabine la raza y la etnicidad, que habían comenzado en la década anterior, adquirieron su mayor densidad acompañados por las reformas constitucionales que convirtieron

• The type of ventricular arrhythmia monomorphic

  2019-06-26

  

  The type of ventricular arrhythmia (monomorphic VT or polymorphic VT/VF) responsible for the electrical storm provides an important diagnostic clue to its pathophysiology (Fig. 1). In this review, we address the diagnosis and specific treatments according to the type of ventricular arrhythmia and th

• Introduction Atrial fibrillation AF is a common cardiac arrh

  2019-06-26

  

  Introduction Atrial fibrillation (AF) is a common cardiac arrhythmia that becomes more prevalent with age [1] and is associated with an increased long-term risk of stroke, HATU structure failure, and all-cause mortality [2]. Since Einthoven recorded the electrograms in 1906 [3], AF has widely been

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