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In recent years there has
2019-06-11

In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mR
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A critical link exists between awareness of risk the presenc
2019-06-11

A critical link exists between awareness of risk, the presence of disease, and steps taken by the patient and clinician to change the natural history of disease. Chronic illnesses such as diabetes mellitus, dyslipidaemia, anaemia and a multitude of endocrinological and rheumatological diseases are r
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There are several limitations to the procedure described
2019-06-11

There are several limitations to the procedure described herein. The present GC was developed for engaging the coronary sinus via a right-sided approach. However, this GC was bent dorsally and had the shortest tip and most acute tip angle among the Attain™ family, which facilitated its placement int
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Combined use of two AADs was more frequent
2019-06-10

Combined use of two AADs was more frequent in persistent (6.7%) and LS-persistent AF (7.5%) patients than in PAF patients (2.8%, pdifferent SW033291 prescribed at the time of discharge in the three AF types. The choice of bepridil was dependent on the type of AF (PAF 10.6% vs. non-PAF 30.3%, p Dis
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MADIT trial enrolled adult patients with prior
2019-06-10

MADIT trial enrolled 196 adult patients with prior myocardial infarction more than 3 weeks (Q wave or elevated cardiac enzyme), with non-sustained ventricular tachycardia (a run of 3–30 of ventricular ectopic beats with a rate more than 120 beats per minute), with left ventricular ejection fraction
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The diagnosis is very difficult on radiographical imaging al
2019-06-10

The diagnosis is very difficult on radiographical imaging alone as many tumours have similar radiological appearances to desmoplastic fibroma [2,7]. Biopsy is the gold standard method of determining the exact nature of any bony lesion as it provides a tissue diagnosis. The biopsy ideally should be p
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In this case series no clinical thromboembolic events were d
2019-06-10

In this case series, no clinical thromboembolic events were detected in a cohort with a mean CHA2DS2-VASc score of 2.6 ±1 over a follow-up time of up to 5 years. The overall stroke rate was 0.5% per year. The authors concede that the very low stroke rate could have been the outcome of successful abl
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bupropion hydrochloride cost In Blake Alkire and colleagues
2019-06-10

In , Blake Alkire and colleagues now provide additional measures to help us gain political priority on the public health agendas. In this study, Alkire and colleagues modelled access to surgery in 180 countries on the basis of four criteria: timeliness, surgical capacity, safety, and affordability.
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br CONSIDERACIONES FINALES Como se infiere de los
2019-06-10

CONSIDERACIONES FINALES Como se infiere de los ejemplos revisados en el apartado anterior, podríamos decir que esta suerte de homenaje póstumo concretado en las notas necrológicas de la RF está destinado abscisic acid figuras intelectuales que sintonizan con la orientación ideológica de la public
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Prior case reports have described hematological
2019-06-10

Prior case reports have described hematological remission in patients with myelofibrosis during treatment with bisphosphonates, but a phase II study investigating the effects of zoledronic purchase ARQ 621 on patients with myelofibrosis showed responses in only 1 of 16 patients[13]. In conclusion,
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With the availability of vaccines
2019-06-10

With the availability of vaccines, screen-and-treat approaches, and effective drugs to treat hepatitis C virus, , and HIV infections, the question is no longer limited to what to do but now extends to how to implement. The expanding focus from basic research, drug development, and clinical trials th
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Data continue to show increasing numbers of facility
2019-06-10

Data continue to show increasing numbers of facility-based deliveries with an appreciable decline in both maternal and newborn baby deaths. With nearly half of all births being delivered in low volume, primary health facilities, these facilities clearly fulfill a very crucial role in ensuring that p
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br After several decades of community based interventions an
2019-06-10

After several decades of community-based interventions and surveillance, on Nov 15, 2016, Morocco was recognised by WHO as having eliminated trachoma as a public health problem. A formal ceremony, involving the handover of a letter of recognition from Margaret Chan, WHO\'s Director-General, marked
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br Acknowledgments We thank all the
2019-06-10

Acknowledgments We thank all the ultramarathon runners who participated in this study and all the doctors, nurses, and emergency medical technicians who provided professional care at the ultramarathon race. We also thank our colleagues at Soochow University, Taipei, Taiwan and the Chinese Taipei
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Since BM impairs the balance between bone formation
2019-06-10

Since BM impairs the balance between bone formation and bone resorption, altered bone remodeling activities can be assessed directly by measuring the components of affected bone cells or indirectly by analyzing metabolic products released from the bone matrix by changed rates of bone formation or r
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