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Introduction Antimicrobial peptides AMPs are a group of
2018-10-30
Introduction Antimicrobial peptides (AMPs) are a group of biomolecules that have evolved to recognize and kill target microbes by binding to and disrupting cell membranes. Several unique characteristics of AMPs make them attractive alternatives to antibodies for detection of microbial biothreats: r
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br Design methods and materials br
2018-10-30
Design, methods and materials Results Discussion and conclusion We proposed and demonstrated a biosensing platform utilizing circular current lines fabricated on the sensing area and fluorescent magnetic nanoparticles as labels. The current line design provides excellent control over the mo
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En la Argentina industrial fue reemplazada con violencia por
2018-10-30
En 1976, la Argentina industrial fue reemplazada, con violencia, por el modelo neoliberal de renta y financiero, que rigió hasta el derrumbe de la convertibilidad cell cycle arrest principios de 2002. Sus principales características fueron: endeudamiento externo, dependencia de Estados Unidos, redis
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Durante cinco meses atroces el Estado
2018-10-30
Durante cinco meses atroces, el Estado griego debió pedir prestado buy SAR405 tasas usurarias hundiéndose cada vez más en la insolvencia, aunque proclamando que podía atravesar la tempestad. La canciller Merkel parecía dispuesta a dejar hasta el último momento que Grecia se desenvolviera sola para e
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Alemania dict a los otros pa
2018-10-30
Alemania dictó tranylcypromine los otros países europeos las condiciones (o reglas) bajo las cuales iba a abandonar su adorado deutschemark y convertir la Bundesbank en una franquicia del bce. Una de las condiciones es que toda Europa se someta a un pacto de estabilidad. Berlín quería una moneda úni
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br Situaci n actual de la seguridad social
2018-10-30
1. Situación actual de la seguridad social El sistema de seguridad social actual en México presenta anomalías importantes relacionadas con la fragmentación, desarticulación y deficiencias en la coordinación institucional, la duplicidad de programas públicos y de beneficiarios, la pérdida en el ap
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In another line of research Arida et al
2018-10-30
In another line of research, Arida et al. (2005), Lara Resende (2006) e Arida (2006), among others, called the attention to the risk of jurisdictional uncertainty in Brazil. Arida et al. (2005), for instance, argue that the inexistence of a local long-term domestic credit market could be seen as a m
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The second strand is the literature on capture Laffont
2018-10-30
The second strand is the literature on capture. Laffont and Tirole (1991) developed the three-layer model to study collusion between a privately-informed agent and intermediates employed by the principal to bridge the informational gap. They showed that the principal may benefit from this arrangemen
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cyclooxygenase-2 inhibitors We also examined ovarian cancer
2018-10-30
We also examined ovarian cancer mortality; in the high exposure period, the RR reduced to 0.62 (95% CI 0.38–1.02; 2-tailed p=0.06). Since with ovarian cancer we had a clear a priori hypothesis that mortality might be reduced based on our breast cancer findings, we also calculated a 1-tailed test of
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In agreement with others we found that
2018-10-30
In agreement with others, we found that short periods of hypothermia have negligible effect on basal viability, but reduce cell injury in the face of oxidative stress (Antonic et al., 2014; Rzechorzek et al., 2015). Our multiplexed injury analysis (Rzechorzek et al., 2015) also addresses previous li
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Several conflicting large scale population based studies pub
2018-10-30
Several conflicting large-scale population-based studies published recently (e.g. (Lau et al., 2015; Moriya et al., 2015; Tsunoda et al., 2014)) indicated that rolipram moderate (or ‘non-alcoholic’) alcohol consumption either has a beneficial or detrimental association with prevalence or developmen
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Additionally we showed that treatment with the same
2018-10-30
Additionally, we showed that treatment with the same AntagoNAT induced SCN1A upregulation in human cells with different mutation types (Fig. 11), thus opening the possibility of using one AntagoNAT for the treatment of many Dravet patients, as opposed to designing a separate molecule for each mutati
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caffeic acid Our systematic review demonstrated that the maj
2018-10-29
Our systematic review demonstrated that the majority of NOD2-smoking studies were underpowered to detect an interaction; for example, 10 identified studies included fewer than 300 participants (de Diego et al., 2006; Giachino et al., 2004; Laghi et al., 2005; Mardini et al., 2005; Mendoza et al., 20
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Oversized preliminary clusters were selected for subsequent
2018-10-29
Oversized preliminary clusters were selected for subsequent splitting by agglomerative hierarchical clustering based on a criterion of (mean number of marked minutiae per examiner) >1.5. This arbitrary threshold was selected because (1) automated splitting of clusters meeting this criterion was high
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One explanation of the small
2018-10-29
One explanation of the small learning effects of free writing in our study is that the task of writing Chinese characters is more cognitive-resource consuming than writing a letter. Writing characters involves greater demands on visual-spatial working memory, and writing ability itself is constraine
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