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br Conflict of interests br Acknowledgments
2018-10-25
Conflict of interests Acknowledgments We gratefully acknowledge all the staff who participated in this study. This work was supported by Grants from National Natural Science Foundation of China (No. 81460323). Introduction Respiratory tract infection (RTI) is a common disease in all ages o
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The mdx mouse is a naturally occurring genetic
2018-10-24
The mdx mouse is a naturally-occurring genetic and biochemical homologue of DMD and has been widely used as an experimental model. Although mdx muscles retain their capacity to regenerate throughout life, certain muscle in old mdx mouse, including diaphragm (Stedman et al, 1991), soleus and plantari
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The dedifferentiation of lineage committed cells into more p
2018-10-24
The dedifferentiation of lineage-committed tamoxifen citrate into more primitive stem-like states during transplantation is similar to the cell-state transitions that occur during tumor initiation (Keller et al., 2010). For example, preceding the onset of basal cell carcinoma, adult tumor-initiatin
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Local connectivity was assessed in animals pre injected with
2018-10-24
Local connectivity was assessed in animals pre-injected with lentiviral vectors into the striatum prior to grafting (Figure 4A). In these animals, a widespread mCherry expression in host striatum was observed (Figures 4B and 4C), and a distinct mCherry− graft core could be easily delineated (Figures
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As an initial application of our RNA seq datasets
2018-10-24
As an initial application of our RNA-seq datasets for discovery of regulatory mechanisms in huSCs, we compared transcriptomes of quiescent huSCs to those of activated huSCs to identify loci that were differentially expressed. In quiescent huSCs, we identified 998 highly expressed genes, including 13
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br Results br Discussion Inconsistencies among
2018-10-24
Results Discussion Inconsistencies among cell source isolation and reprogramming techniques can result in iPSCs that may appear similar, but have very different capacities to modulate or contribute to tissue regeneration (Bar-Nur et al., 2011; Hiler et al., 2015). In addition, several studies
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One possible explanation for the
2018-10-24
One possible explanation for the differential behavioral improvements in the three distinct HD mouse models could be the different cell survival rate with the highest survival rate in QA-lesioned animals. NPCs transplanted into transgenic animals generally displayed lower cell survival, a phenomenon
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Intriguingly consistent with previous studies Wong
2018-10-24
Intriguingly, consistent with previous studies (Wong et al., 2011; Enver et al., 2005; Haurie et al., 2010), our data show that POLR3G is highly expressed in pluripotent stem order LJI308 and is required for maintenance of the pluripotent state. However, the mechanisms by which how POLR3G contribut
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JmjC domain containing histone demethylase C JMJD C
2018-10-24
JmjC domain-containing histone demethylase 2C (JMJD2C) is a histone lysine demethylase (HDM) specific for histones H3K9me3, H3K9me2, and H3K36me3 (Cloos et al., 2006; Klose et al., 2006; Whetstine et al., 2006). HDMs are histone-modifying enzymes with biological functions opposite to those of HMTs.
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br Conclusions The co precipitation method was successfully
2018-10-24
Conclusions The co-precipitation method was successfully employed for the preparation of potential TLD and OSLD SrSO4:Eu2+ phosphor. The XRD profile of SrSO4:Eu2+ was in good agreement with the ICDD file. The comparison of TL and OSL sensitivities showed that the former for SrSO4:Eu2+ was 100 tim
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Aside from yield point change structural element
2018-10-24
Aside from yield point change, structural mek inhibitors refinement can also affect the melting temperature. The latter is determined experimentally for micro- and nanodisperse materials, but not as definitively as the yield point. For example, aggregate and powder metallic nanomaterials may have d
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Introduction The research of hydrogen
2018-10-24
Introduction The research of hydrogen ep4 in solids is of great practical value. The phenomena of hydrogen embrittlement and casting cracking during cooling and crystallization occur as a result of hydrogen diffusion. Gorsky proved in Refs. [1,2] that crystalline matrix deformations occurring due
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The molecular dynamic investigation of
2018-10-24
The molecular dynamic investigation of the fluoxetine hydrochloride characteristics in nanocrystalline materials through the sum of squared atomic displacements has been successfully used by us in the studies in grain boundary self-diffusion in the high-purity copper and the diffusion of copper alon
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and the corresponding values of the
2018-10-24
and the corresponding values of the universe\'s volume: with , which implies the constraint Eq. (16). Corresponding eigenfunctions are the following [20]: Inflation as the birth of the space quanta So then, we suppose that the state of minimal excitation of space (15) is the initial proto-infla
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Introduction One of the central goals
2018-10-24
Introduction One of the central goals of mi2 health science is to achieve equitable health distributions within populations, while seeking to maximize overall population health (Keyes & Galea, 2016). However, the impact of health policies and programs is often not distributed equally throughout a
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