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br Empirical application public health services supply
2018-10-23
Empirical application: public health services supply Methodology: demand However, to guarantee the robustness of our results, we should divide municipalities into different groups according to at least a different classification other than size. In fact, in Section 7, we use the grouping of mu
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In used WGS to investigate
2018-10-23
In , used WGS to investigate a 40-year meningococcal disease pandemic caused by the hyperinvasive ET-5/ST-32 complex. A global collection of forty-three isolates, including 14 different MLST STs, cultured from 1969 to 2008 was investigated, to set a baseline for the hyperinvasive ET-5/ST-32 compl
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Understanding how barrier tissues function
2018-10-23
Understanding how barrier tissues function is essential for the design of effective pharmaceutical compounds. Once these devices are transitioned from research to clinical use, and we have more accurate predictive models early on in the development process, we will likely see an end to the recent st
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br Author Contributions br Disclosure br Acknowledgements
2018-10-23
Author Contributions Disclosure Acknowledgements We are grateful to J. De Rijck for critical reading and thank P. Van de Velde, B. Vanremoortel and NJ. Van der Veeken for their technical assistance. Viral vector production was performed at the Leuven Viral Vector Core. LEDGINs were synthesi
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Invasion of the subarachnoid space by causes a strong
2018-10-23
Invasion of the subarachnoid space by causes a strong inflammatory cascade orchestrated by the innate immune system involving several receptors like Toll-like receptors (TLR) as well as various cytokines and chemokines (). It is an important question whether genetic variations of the innate immune
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br Tuberculosis is an infectious
2018-10-23
Tuberculosis is an infectious disease which can be treated better when the applied dose of the anti-tuberculosis drug is optimal. The basic antituberculosis drug isoniazid (INH) was one of the first medical drugs for which individual differences in the metabolism were reported more than 50years ag
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Recently we focused our research on a different aspect of
2018-10-23
Recently, we focused our research on a different aspect of immune function, at the intersection of immunity and genetics, namely on the Human Leukocyte Antigen (HLA) (Georgopoulos et al., 2015). HLA genes are located in the Major Histocompatibility Complex (MHC) of chromosome 6 and play a central ro
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These findings challenge in some ways previous work and
2018-10-23
These findings challenge in some ways previous work and underpin alternative hypotheses to link insulin resistance and NP deficiency. One first possibility is that NP deficiency requires additional factors than insulin resistance only. This may include hyperglycemia and low-grade inflammation. This
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br Results The analyses included AF
2018-10-23
Results The analyses included 1116 AF patients with history of stroke or TIA at baseline (Fushimi AF registry, n=688; Darlington AF registry, n=428). The secondary prevention AF patients in the Fushimi registry were significantly younger, with fewer females and less likely to have hypertension an
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The following are the supplementary data related to this
2018-10-23
The following are the supplementary data related to this article. Conflict of Interest Author Contributions Acknowledgments This work was supported by The Hormel Foundation and National Institutes of Health grants CA187027, CA027502, CA196639, and CA16601. We thank Dr. Robert H. Whitehead
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br Ethic approval br Acknowledgments This work was supported
2018-10-23
Ethic approval Acknowledgments This work was supported by the Karlsruhe Institute of Technology (KIT), the Deutsche Forschungsgemeinschaft (DFG Str439/5-1), the Association Française contre les Myopathies (AFM), EU-IP ZF-HEALTH. Data The data shared in this article are the experimental ana
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br Experimental design materials and methods br Acknowledgme
2018-10-23
Experimental design, materials and methods Acknowledgments This work was supported by the project “Seeding production of eel Anguilla japonica by artificial induction of sexual maturation” (R2016011) of the NIFS, Korea, and the Export Strategical Item of KIMST, Korea. Data The dataset pres
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ahr pathway Reentry studies performed on lifting body config
2018-10-22
Reentry studies performed on lifting-body configuration have focused mainly on crew return vehicles (CRVs) [4], while the research on wing-body configuration is focused on orbital space planes and maneuverable reentry vehicles [10–13]. Li et al. [14,15] carried out trajectory optimization of a boost
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tlr inhibitor In previous papers global IED effects and poss
2018-10-22
In previous papers, global IED effects and possible protection concepts were discussed [1,2,7,9]. This work is based on these results and summarises them in a form of an engineering software tool called PVIED (Protection of Vehicles against IED). The emphasis was put on modelling the momentum transf
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La corriente del psicoan lisis que se
2018-10-22
La corriente del psicoanálisis que se desarrolló en Estados Unidos se apegó dacomitinib la teoría de las relaciones objetales, la cual dio prioridad al yo, haciéndolo el centro de la realidad del sujeto. Desde dicha perspectiva, se equipara al yo con una especie de conciencia, por lo que el tratamie
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