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br Conclusion and future prospects The research
2018-10-22
Conclusion and future prospects The research on M. oleifera is yet to gain importance in India. It is essential that the nutrients of this wonder tree are exploited for a variety of purposes. M. oleifera has great anti-diabetic and anti-cancer properties. However, double blind researches are less
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br Results br Discussion Cell therapy using
2018-10-22
Results Discussion Cell therapy using hESCs has received a great deal of attention following the initial hESC culture techniques reported in 1998 (Thomson et al., 1998). However, the application of hESCs in clinical cell therapy is limited because current culture conditions have certain disadv
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The interaction between intact AM and limbal explants does n
2018-10-22
The interaction between intact AM and limbal explants does not only degrade the matrix of the AM but also activate intracellular signaling cascades triggered by matrix components. By use of selective pharmacological inhibitors, we investigated the downstream effectors critical for intact AM-induced
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Adipose tissue derived mesenchymal stem cells AT MSC
2018-10-22
Adipose tissue derived mesenchymal stem retinoic acid receptor (AT-MSC) are an easily available autologous source of multipotent cells for cell therapy applications (Pittenger et al., 1999; Zuk et al., 2002). Like HSC, MSC derive from embryonic mesoderm. When cultured in hematopoietic differentiati
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br Experimental Procedures br Acknowledgments We are gratefu
2018-10-22
Experimental Procedures Acknowledgments We are grateful to S. Yamanaka (University of Kyoto) for providing the plasmid and retroviral vectors through Addgene, and to T. Kitamura (University of Tokyo) for providing PlatE cells. We thank A. Nifuji, H. Ideno, and T. Kamada for helpful discussions
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D-Luciferin JNK signaling promotes the expression of cytopro
2018-10-22
JNK signaling promotes the expression of cytoprotective genes in flies, which contributes to tissue homeostasis loss in aged guts (Biteau et al., 2008). We found that JNK activity was increased in dbr- and ptc-depleted guts, and further inhibition of JNK activity in these guts effectively suppressed
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Disorganized actin fibers can limit cell migration Spallaros
2018-10-22
Disorganized hexokinase regulation fibers can limit cell migration (Spallarossa et al., 2010). The formation of disorganized actin fibers indicates a rearrangement of the cytoskeleton and, therefore, can be independent of directed F-actin stress fibers (Jaalouk and Lammerding, 2009). As demonstrate
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br Materials and methods br
2018-10-22
Materials and methods Results Discussion To the best of our knowledge, the present study constitutes the first report describing diet-mediated inhibition of the expansion of the MaSC-enriched (CD29hiCD24+Lin−) epithelial subpopulation in vivo that may relate to decreased susceptibility to m
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angiotensin ii receptor blockers br Stimulation of the myoca
2018-10-20
Stimulation of the myocardial endogenous regenerative capacity for damage repair Most severe cardiac diseases are due to a deficit of contractile cells, the myocytes, in number, function or both. Therefore, most approaches to repair myocardial damage are designed to replace the lost or dysfunctio
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br Materials and methods br Results br
2018-10-20
Materials and methods Results Discussion Human olfactory stem cells can be grown in neurospheres (Reynolds and Weiss, 1992). Murrell et al. obtained human mucosa by biopsy and generated OSs. They separated olfactory mucosa into lamina propria and epithelium. After separately dissociated, ce
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It has recently been shown that murine IHBD and
2018-10-20
It has recently been shown that murine IHBD and EHBD systems develop from distinct stem E-4031 manufacturer (Spence et al., 2009). In addition, we have found adult mouse gallbladder stem cells to be unique or distinct compared to IHBD cells (Manohar et al., 2011). We therefore chose to evaluate the
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Interferons are a diverse family of
2018-10-20
Interferons are a diverse family of cytokines which possess antiviral and immunomodulatory properties (Isaacs and Lindenmann, 1957; Stark et al., 1998; Theofilopoulos et al., 2005). These specialized proteins are produced by cells in response to viral infection. Cellular sensors such as retinoic con
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br Introduction During early embryogenesis ectoderm differen
2018-10-20
Introduction During early embryogenesis, ectoderm differentiates into surface ectoderm, neural crest, and neural tube. From the surface ectoderm, oral ectoderm and skin develop [1]. In turn, the oral ectoderm differentiates into the adenohypophysis [2,3], dental epithelia [1], salivary glands [1]
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br Materials and methods br Results br
2018-10-20
Materials and methods Results Discussion The current work showed that M3O-SKM allows for the establishment and maintenance of iPSCs in the absence of exogenous LIF. We also showed that miR-205-5p synergizes with M3O-SKM. More than 20 individuals or families of miRNAs play critical roles in
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br Materials and methods br Author disclosure
2018-10-20
Materials and methods Author disclosure statement Acknowledgments We are grateful to Prof. Angel Raya for his help and advice with iPS cell generation. This work was supported by grants from the “Centro de Investigación Biomédica en Red en Enfermedades Raras” (CIBERER) (grant 13-717/132.05
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