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The expression profiles of NCK and ABI genes
2021-07-23
The expression profiles of NCK and ABI genes after ESC bacterial infection were determined. As shown in Fig. 1a, NCK1, ABI2a and ABI2b were significantly induced after ESC infection. While, ABI3a was significantly downregulated. Intestine was confirmed as a site of E. ictaluri entry by bacteriologic
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Abbas et al studied the mitigation
2021-07-23
Abbas et al. studied the mitigation of ASR in their corresponding study by incorporating RHA [1]. These researchers used Ordinary Portland Cement (OPC), four different percentages (i.e., 10%, 20%, 30% and 40% by weight of OPC) of RHA and reactive aggregate (sand from Dolomite-limestone rock) in thei
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Another clinical study indicated the daily consumption of gr
2021-07-23
Another clinical study indicated the daily consumption of green tea with low concentrations of theanine and catechin would improve cognitive function (Ide et al., 2014). Further, in a double blind randomized clinical study involving 102 patients, the Hypericum extract was examined in terms of effica
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A factor that complicates the use of human
2021-07-23
A factor that complicates the use of human liver M871 is one of variability, which arises in part because many of the human liver samples available for research show various stages of a variety of disease states (steatosis (fatty liver), cirrhosis, carcinogenesis in adjacent tissue), although care
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br Methods br Results br Discussion With this
2021-07-23
Methods Results Discussion With this study, we provided evidence that acriflavine can interfere with EMT and UPR, two well-described pathways associated with cancer aggressiveness. And, because drug resistance is also clearly associated with the mesenchymal state [36], blocking of the epith
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br Concluding Remarks Recent studies have provided unprecede
2021-07-23
Concluding Remarks Recent studies have provided unprecedented details of APC/C structure and enzymology, which explain how the activity of this massive E3 ligase is controlled, and how ubiquitylation is achieved to temporally regulate cell division. Although one pervasive question has been why th
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Advances in the total chemical synthesis
2021-07-23
Advances in the total chemical synthesis of ubiquitin have enabled the efficient synthesis of new and improved ubiquitin-based reagents. Using an optimized linear synthesis, ubiquitin can now be easily obtained in high yield and purity [35]. Using this synthetic methodology, ubiquitin can be functio
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Neurons in the striatum unlike those in the cerebral
2021-07-23
Neurons in the striatum, unlike those in the myosin inhibitor and cerebellum, do not form a layered or columnar structure. Although they appear to be randomly distributed, they are actually scattered in two embryologically different compartments called striosomes (often referred to as “patches” in
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Furthermore Survivin is a member of the
2021-07-23
Furthermore, Survivin is a member of the inhibitor of apoptosis family. IR induces a rapid nuclear accumulation of survivin and subsequent phosphorylation of the protein in the nucleus. Co-immunoprecipitation and immunofluorescence co-localization analyses revealed an interaction among survivin, Ku7
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Then what is the solution to
2021-07-23
Then what is the solution to tackle DNA damage-induced metabolic decline? The culprit here may be not DNA damage signaling per se, but rather the persistent activation of the DNA damage signaling pathways due to age-related accumulation of DNA damage. DNA repair, including repair by NHEJ, is an esse
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We elucidated that the ten DGK isozymes have different
2021-07-23
We elucidated that the ten DGK isozymes have different relative 1-MGK and 2-MGK activities vs DGK activity under the same conditions. However, because the octylglucoside-mixed micellar assay was developed for DGK, it is not known whether the DGKs exhibit maximum 1-MGK and 2-MGK activities in this as
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br Materials and methods br Results Because of the
2021-07-23
Materials and methods Results Because of the specific binding of DGKε to an arachidonoyl group, there was a particular interest to evaluate the behavior of 2-AG with this isoform of DGK. The substrate specificity and kinetic constants for DGKε has been recently reported [13]. Using the preferr
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br Role of cysLT signaling
2021-07-23
Role of cysLT signaling on various neurological complications which are associated with Alzheimer’s disease Alzheimer’s disease, first described in 1906 by Alois Alzheimer, is a neurodegenerative disease and a very common cause of dementia progressively leading to death. Even though years of rese
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Methylated CpGs can recruit transcriptional
2021-07-22
Methylated CpGs can recruit transcriptional co-repressors to prevent transcription factors (TFs) from promoting gene expression by tightly packing 5ht structures [38]. Two CpG islands in the IPT5b promoter region showed higher methylation level in M9 rootstock compared to Mr (Fig. 3b). However, IPT5
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Park et al expanded their
2021-07-22
Park et al. [34] expanded their own model as hydrogen- bonding lattice fluid EOS (NLF-HB) [35] for calculating the activity coefficients of aqueous amino im 12 solution. Further, Pazuki et al. [36] extended the perturbed hard chain theory which has been proposed by Beret and Prausnitz [37] for mode
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