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For statistical analysis the Statistical
2019-07-02
For statistical analysis, the Statistical Package for Social Sciences (SPSS) was used (version 21.0; SPSSInc., Chicago, IL). Chi-square (x2) exact test was used for the comparison of categorical data, whereas Wilcoxon and Mann–Whitney U tests were used for the analysis of nonparametric variables bas
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A phenylacetic acid derivative discovered
2019-07-02
A phenylacetic AS-1404 derivative (), discovered in a high throughput screen for CRTH2, inhibited the binding of H-PGD to CRTH2 receptors on 293 cells with an IC of 0.010μM, and inhibited the binding of H-PGD to DP receptors with an IC of only 8.3μM (). Compound also inhibited CRTH2 mediated cell
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Behaviors were compared between saline and amphetamine pre t
2019-07-02
Behaviors were compared between saline and amphetamine pre-treatment groups at 24h and 2 weeks following the last treatment, or between pre-treatment groups that received vehicle or ASV-30 infusions, using separate two-way ANOVAs. Significant effects were analyzed further using Student–Newman–Keuls
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Citrus comprising some of the most widely cultivated fruit
2019-07-02
Citrus [29], comprising some of the most widely cultivated fruit crops worldwide, has been consumed as a food and dietary supplement. According to traditional Chinese medicine, dry pericarp of Citrus, as a Chinese herbal remedy, is capable of regulating Qi and expelling phlegm, and has been used to
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Dioscin br Experimental br Results and discussion On the bas
2019-07-02
Experimental Results and discussion On the basis of the information obtained from the studies on RHA/TiO2 nanocomposites, it Dioscin is expected that this reagent can be used as a catalyst for the promotion of the organic reactions. So this reagent was used in the promotion of the conversion o
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The relatively low overall response rates
2019-07-02
The relatively low overall response rates suggest the need for better predictive markers for response. The patient demographics in the SARC trial did not reflect typical Ewing sarcoma demographics as the patients tended to be older and had primarily soft tissue tumors. In addition, although accrual
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br Materials and methods br Results br Discussion PKA and
2019-07-02
Materials and methods Results Discussion PKA and Epac are two principal effector proteins involved in cAMP signaling; they are expressed in a wide range of tissues and control diverse biological functions [10]. The existence of two cAMP effectors provides more precise regulation of cAMP sig
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N Cyclopentylmethyl analog exhibited fold
2019-07-02
N-Cyclopentylmethyl analog 25 exhibited 2.3-fold less potent receptor affinity and 1.6-fold less potent antagonist activity. Among the compounds tested, the N-isobutyl analog 23 showed the most potent EP1 receptor affinity and antagonist activity. In summary, a series of 4-( 2-[alkyl(phenylsulfonyl
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Other membrane currents are affected as
2019-07-01
Other membrane currents are affected as well. Some studies have provided evidence that sulfonylureas, in addition to blocking KATP channels, also inhibit chloride and calcium channels. GLYB has been shown to almost inhibit the current generated by Na+–K+ pumps in a concentration-dependent manner (wi
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We analyzed whether HaCaT cells treated
2019-07-01
We analyzed whether HaCaT prostanoid receptors treated with PLD can alter the expression of genes involved in DNA damage response. Key DNA damage cues activate the sensory DNA-PK/ATM/ATR kinases, which relay two parallel cascades that ultimately serve to inactivate the Cyclin B-cdc2 complex. The pr
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br Conclusions br Statement of authorship br
2019-07-01
Conclusions Statement of authorship Nonaneurysmal subarachnoid hemorrhage (NA-SAH) differs from aneurysmal subarachnoid hemorrhage (SAH) in both clinical course and outcome. In spite of many reports and case series since the first description in 1985, the etiology of NA-SAH remains uncertain
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One study reported the role of the Purkinje
2019-07-01
One study reported the role of the Purkinje system with respect to the relationship between the septum and HCM-related VT. Santangeli et al. reported that patients with HCM also often have His-Purkinje conduction-related septal abnormalities, and bundle branch block often develops as part of the nat
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Clinical genetic electrocardiographic and electrophysiologic
2019-07-01
Clinical, genetic, electrocardiographic, and electrophysiological variables did not differ significantly between patients with and without the ER pattern (Table 2). Discussion Among our Brugada syndrome patients, the prevalence of the ER pattern was 10.1%, which is high in comparison to the 2%–5
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A recent analysis recommended axillary staging by sentinel l
2019-07-01
A recent analysis recommended axillary staging by sentinel lymph node biopsy, and administration of adjuvant radiotherapy and endocrine therapy after breast conserving surgery for mucinous carcinoma. Park et al. concluded that adjuvant chemotherapy could potentially be omitted in cases with favorab
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br Introducci n De una manera muy
2019-07-01
Introducción De una manera muy esquemática y TAK-242 grandes trazos, podemos diferenciar al menos cuatro momentos en los estudios sobre la democracia en América Latina en el último medio siglo, según algunos problemas predominantes. Las limitaciones y quiebres democráticos, las posteriores transi
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